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LEAD INVESTIGATOR

5.00 to 6.00 Years   Chennai   10 Feb, 2021
Sygene
Job LocationChennai
EducationNot Mentioned
SalaryNot Disclosed
IndustryPharma / Biotech
Functional AreaOperations Management / Process Analysis
EmploymentTypeFull-time

Job Description

The group primarily focuses on creating, validating and implementing IHC-based assays in the early clinical translational research space to generate critical data that support.1) mechanism of action hypotheses, 2) pharmacodynamic evaluations, and 3) identification of novel biomarkers related to clinical response. The team is also responsible for delivering on all outsourced clinical samples needing IHC endpoints including vendor management and quality oversight

  1. Members of the team are also deeply engaged in new technology identification and evaluations, including multiplexed IHC, digital image analysis, deep learning and other emerging technologies critical to the continued scientific leadership of BMS.
  2. The group works closely with the pharmacodiagnostics team to transfer assay methods to diagnostic companies for companion/complementary diagnostic development.
  3. Members of this team work on various projects in concert with multiple groups including oncology development teams, translational biology, biomarkers and pharmacodiagnostics.
  4. Additional key responsibilities include transferring and overseeing the execution of IHC work at external partners, and collaborating to provide technical expertise and analytical guidance for critical academic partnerships with BMS
  5. Additionally, the team is responsible for keeping current with advanced technologies related to tissue-based assays, including multiplex immunofluorescence, laser microdissection, spatial transcriptomics, advanced digital pathology, image analysis and deep learning
1) This position requires a PhD and/or MD, or their foreign equivalents, and demonstration of scholarly productivity in a relevant field of biomedical research.2) Preference will be given to individuals with hands-on experience or experience in applying advanced digital microscopy and software methods for quantitative assessment of IHC results.Qualified candidates must have at least 5 years work experience (clinical, academic and/or biopharma). Preference will be given to individuals with previous experience in the field of oncology and immunology biomarkers.Prior management experience is considered a plus, but not required.Prior experience with clinical studies and diagnostic development is a plus.Successful candidate will be a highly motivated and collaborative, with a demonstrated capacity to multitask and work across disciplines in a complex matrix organization.Excellent written and verbal communication skills and the ability to clearly communicate scientific objectives and project results are required.Strong understanding and track record of developing and implementing strategic initiatives that improve scientific and/or operational activities. Familiarity with the techniques common to translational research including flow cytometry, genomics, proteomics and data analysis.Ability to interact well with managers to help develop and execute a strategy for translational research.Understanding of good clinical laboratory practices is preferred.Strong understanding with CAP/CLIA regulations a plus.,

Keyskills :
flow cytometryemerging technologiesimage analysisvendor managementlaserstrategic initiativestranslational researchdeep learningvendorassaydigital pathology

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