Section Head, In Vivo Pharmacology, Discovery Biology

Job Description

Designation: Section Head- In Vivo Pharmacology, Discovery BiologyJob Location: Bengaluru, Karnataka, IndiaReporting To: VP, Discovery BiologyAbout Syngene:Syngene International Ltd. (BSE: 539268, NSE: SYNGENE, ISIN: INE398R01022), is an integrated research, development, and manufacturing solutions company serving the global pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical sectors. Syngene s 4500+ scientists offer both the skills and capacity to deliver great science, robust data management and IP security, and quality manufacturing at speed, to improve time-to-market and lower the cost of innovation. With a combination of 1.9 Mn sq ft of specialist discovery, development and manufacturing facilities, as well as dedicated research facilities for Amgen, Baxter, Bristol-Myers Squibb and Herbalife, Syngene works with biotech companies pursuing leading edge science as well as multinationals including GSK and Merck KGaA.Job Role Syngene is seeking a highly talented individual with strong leadership skills and experience in drug discovery, for a Section Head role within Discovery Biology (DB). The Section Head, In vivo pharmacology will be responsible for the scientific and operational excellence, as well as commercial competitiveness, of the In Vivo Pharmacology department. The Section Head will report directly to the VP, Discovery Biology Solutions, with a focus on preclinical therapeutic discovery and development. The successful candidate must demonstrate exceptional abilities to lead, manage, and mentor colleagues through matrixed authority, while fostering a spirit of collaboration across each of the technical and enabling functions. The Section Head will drive discovery-related capability development and execution over a range of therapeutic areas and modalities, from the earliest stages of target identification and validation through to candidate selection, preclinical evaluation, and the preparation of IND-ready data packages. The Section Head will have extensive, direct client engagement, be accountable to achieve client goals in the most scientifically rigorous and expedient manner possible, in accordance with Quality and Regulatory requirements. Equally importantly, the candidate must engage in and contribute to Syngene s standard of excellence in Safety, Integrity, Quality, and Compliance (SQIC) policies and metrics. Finally, the Section Head must ensure that the health and growth of Discovery Biology and Discovery Services translates directly into broader benefit across the entire Syngene organization through contributions to Syngene s strategy, people management, capability building, and financial growth. Primary Responsibilities:

• Develop a framework to attain and sustain globally competitive service delivery within the In vivo pharmacology division.
  • Structure the In vivo Pharmacology section for maximum influence and efficiency
  • Build a world-class in vivo pharmacology division with emphasis on pharmacodynamic, disease and translational models, including humanized models.
  • Provide leadership, mentorship, and career development opportunities for scientists in the team
• Augment scientific excellence, operational efficiency, and commercial competitiveness through:
  • Development and implementation of new and enhanced capabilities to more effectively enable therapeutic discovery and preclinical development
  • Active contributions to the Discovery Biology Leadership Forum (DBLF) and Discovery Biology Operations meetings.
  • Enhancing cross-functional collaboration through establishing Core Teams to provide strategic oversight for research projects and initiatives
  • Coordinating the conception, initiation, execution, tracking, and ongoing maintenance of key initiatives
  • Ensuring sufficient skills and an efficient process both for globally competitive scientific proposal writing to gain new business and rigorous technical report writing
  • Ability to take on complex projects and capabilities and to deliver them
  • Set high standards and productivity metrics for the function in the context of continuous improvement for Quality On Time In Full (QUOTIF) and cost-to-serve
• Align and oversee a collaborative framework for In Vivo Pharmacology, EHSS, and E&M to ensure the health and safety of the Discovery Biology workforce through maximizing identification, reporting, awareness, tracking, and resolution of concerns
• Align and oversee a collaborative framework for In Vivo Pharmacology, IT, and Quality to ensure the highest standards of data security, fidelity, longevity, and accessibility are met, with an unwavering focus on data integrity
• Align and oversee a collaborative framework for In Vivo Pharmacology, Business Operations, Finance, HR, and E&M to ensure that the Discovery Biology workforce and infrastructure is appropriately suited to meet current and anticipated demand
• Partner with the Commercial team in the engagement of clients to understand and respond effectively to needs and requirements to meet business objectives
• Partner with the Project Management team in the execution of a collaborative framework of expectations and metrics, clarify and ensure governance, develop pragmatic strategies for execution, track scope changes and progress, and ensure appropriate close-out
• Collaborate with the Finance and Commercial teams to formulate a financial plan including revenue, sales, and profitability targets, and implement the execution plan including clear justification of people, CAPEX, IT and space requirements
• Collaborate with the HR team to promote excellence in employee lifecycle management, including recruitment, onboarding, career development, and retention, with significant emphasis on succession planning at all management levels in the organization. Conduct regular 1:1 meetings with direct reports and their skip levels.
• Overall adherence to safe practices and procedures of all my teams.
• Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company s integrity & quality standards
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self.
• Compliance to Syngene s quality standards at all times.

Additional Responsibilities:

• Act as a leading Syngene spokesperson for Discovery Biology operations meetings, including active participation in Syngene s Safety, Quality and strategic initiatives discussions
• Assist Department head in establishing goals and metrics, as well as tracking
• Assist Department head in the budget roll-up (OpEx, CapEx) across the functions and for key initiatives

Key Qualifications:

• PhD in life sciences with 17 plus years of experience, including in pharma/CRO industry.

Technical/Functional Skills:

• Sound knowledge of drug discovery and of developing phamacodynamic and disease models in rodents and other animal species, including translational and humanized models. Expertise in PK-PD correlations is desirable.
• Courage to think out of the box to solve complex biological problems
• Ability to foster an open, transparent and nurturing environment within the team, where everyone s voice is heard and there is no fear of repercussions.
• Demonstrated leadership, managerial, networking, and collaborative abilities.
• Experience in client relationship management and customer service delivery
• Excellent verbal and written communication skills.

Behavioral Skills:

• A proactive attitude towards internal and external customer satisfaction and the highest standards of scientific quality and regulatory compliance.
• To be an excellent communicator with demonstrable skills in written, spoken and presentation media.
• Have a meticulous attitude towards consistency of 100% quality in study plan, reports and related material.
• Be aware of study status at all times and anticipate problems that may affect timing, quality or integrity and take appropriate action to resolve such problems.

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Keyskills :
new businessclient relationship managementsafetytpmcomplianceisodocumentationanimal healthdata securitylife sciences