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Senior Research Associate - Invitro ADME + Bioanalytical 1

2.00 to 4.00 Years   Delhi   10 Apr, 2023
Sygene
Job LocationDelhi
EducationNot Mentioned
SalaryNot Disclosed
IndustryPharma / Biotech
Functional AreaBio Tech / R&D / Scientist
EmploymentTypeFull-time

Job Description

    • Overall adherence to safe practices and procedures of oneself and the teams aligned.
    • Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company s integrity & quality standards.
    • Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
    • Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
    • Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self.
    • Compliance to Syngene s quality standards at all times.
    Core Purpose of the Role:
    • Bioanalytical scientist familiar in handling HPLC and support ADME screening assays: Formulations analysis, solubility studies, stability studies, ectc. and understanding of LCMS in line with business needs.
    Key Responsibilities:
    • Optimization of test compounds and to develop high throughput, fit for purpose HPLC-UV methods to support ADME samples analysis: Formulations analysis, solubility studies, stability studies, etc.
    • Perform analysis of samples generated for the screening of compounds for ADME assays and Processing of different matrices/formulation samples of PK studies
    • Good written and oral communication skills interacting with internal stakeholders
    • Operation, maintenance and troubleshooting of HPLC/ LC-MS/MS system
    • Preparation of protocols, reports and templates for responsible activities
    • Instrument maintenance, calibration and maintaining documentation as per regulatory requirements and company policy
    • Understanding and demonstrating responsibility for safety of self & colleagues by following all safety protocols provided by Syngene
    • Adherence to all environment, health, and safety (EHS) policies & standards at all times in the workplace
    • Wearing all PPE as required.
    • Adherence to all procedures related to Syngene s data integrity policies
    • Compliance to Syngene s quality standards at all times.
    Syngene Values: All employees will consistently demonstrate alignment with our core values
    • Excellence
    • Integrity
    • Professionalism
    Experience:
    • Minimum 2 to 4 years of relevant industrial experience
    Technical/functional Skills:
    • Hands-on experience in handling of LC-MS/MS systems is mandatory and experience on HRMS is advantageous
    • Expertise in column selection, mobile phase selection, solvent preparations and sample processing techniques such as protein precipitation, liquid-liquid extraction and solid phase extraction
    • Comprehensive understanding of in vitro ADME assays and technical expertise in trouble shooting the assay samples analysis.
    • Basic knowledge on Large molecule and Peptides analysis using LCMS/HRMS
    • Should assist/deliver the scientific presentation in departmental journal club and write official Project reports
    • Should be equipped with quality policies related to data management and data integrity
    Behavioral Skills:
    • Demonstrate ability to be a team player.
    • Commitment to deliver the study reports within the agreed timelines
    • Adaptability to changes in the dynamic lab environment
    • Communicate confidently with colleagues and collaborators in the meetings and presentation of study reports and evidence of publications in the PEER reviewed Journals
    Educational Qualification:
    • M Pharm. in any pharmaceutical science or M Sc. in biological science.
    ,

Keyskills :
in vitrovalidationresearchhplcstudy reports

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