ASSOCIATE SCIENTIST

Job Description

Job Title: Invitro ADME Bioanalyst Job Location: Hyderabad Reporting to: 8-II/7-I Job Grade: Senior Research Scientist (7-II)About Syngene: Syngene is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit.Mandatory expectation for all roles as per Syngene safety guidelines:Overall adherence to safe practices and procedures of oneself and the teams aligned. Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company s integrity & quality standards. Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times. Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace. Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self. Compliance to Syngene s quality standards at all times.Core Purpose of the Role: Optimization of test compounds and to develop high throughput, fit for purpose LC-MS/MS and HPLC-UV methods to support ADME samples analysis: Formulations analysis, solubility studies, stability studies, In vitro assays, MET ID and large molecule analysis etc. Perform analysis of samples generated for the screening of compounds for ADME assays and Processing of different matrices/formulation samples of PK studies with no/minimal supervision Excellent written and oral communication skills interacting with internal stakeholders Operation, maintenance and troubleshooting of HPLC/ LC-MS/MS system Preparation of protocols, reports and templates for responsible activities Instrument maintenance, scheduling calibration and maintaining documentation as per regulatory compliance and company policy Adhering to safety and quality policies laid by organization Delivery of quality data with planning, execution of bioanalytical activities within the team in agreeable timelines Development and implementation of high throughput, fit for purpose bioanalytical methods to support invitro ADME samples analysis Identification of problem and trouble shooting in quick turn-around tim Mentoring team members to generate quality data within agreed timelines To perform MET ID studies and providing final quality data with interpretation Peptide/ large molecule bioanalysis Coordination with related invitro verticals to plan the bioanalysis in cassette Excellent written and oral communication skills interacting with internal/external stakeholders Operation, maintenance and troubleshooting of HPLC/ LC-MS/MS system Preparation of protocols, reports and templates for responsible activities Instrument maintenance, calibration and maintaining documentation as per regulatory requirements and company policy Adhering to safety and quality policies laid by organization Formulation analysis data review and trouble-shooting for quicker resolutionEqual Opportunity Employer: It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.,

Keyskills :
hplcsopequal employment opportunitydocumentationvalidationhigh throughputprotocols