Senior Organic Synthesis Scientist

Job Description

1886! We have more than 130 years of experience treating patients. Sandoz, a division of Novartis, is a global leader in generics and bio-similars and is committed to playing a leading role in improving access to medicines worldwide. Quality is embedded in our daily work, shown by trust and respect of employees, patients and business partner. High quality standards are met in all work processes, in development and production of medicines as well as market supply with our highly qualified and experienced experts playing a key role. As part of our efforts to ensure the quality and safety of our medicines, we are looking for a Scientist in Organic Synthesis to join our team.YOUR KEY RESPONSIBILITIES:Your responsibilities include, but are not limited to: Responsibility for the evaluation of chemical synthesis routes to identify, categorize and control possible mutagenic impurities in active pharmaceutical ingredients (API) and drug products. Assessment of potential degradation pathways of APIs in final drug products with the purpose to identify and assess possibility for the formation of potentially mutagenic impurities and ways to prevent this. Participate in cross- functional technical teams as required to deliver on projects. Involved in paper- based assessment of toxicological data for mutagenic, genotoxic and nitrosamines Conduct of feasibility studies for generic API synthesis and synthesis of by-products, degradation products and related substances. Protection of intellectual property in the field of organic synthesis. Utilize scientific expertise and chemical database to generate solutions to problems. Maintaining laboratory logbooks and other project documents in accordance with good documentation practice (data integrity) and HSE requirements. Co-ordination of laboratory work performed by technicians. Creation of relevant instructions, protocols and reports in accordance with scientific and regulatory standards. Other tasks as assigned by the supervisor and tasks based on a specific appointment. Implementation of and adherence to all the instructions and requirements for safe work, environment protection and property protection. Responsibility for personal and professional development, willingness to continuously learn and enhance the knowledge. Continued education and learning in form of training and mentoring. High integrity and proactive cooperation within local and global teams across different geographies. If needed, to be trained according to SOPs related to GxP.Minimum requirements WHAT YOU LL BRING TO THE ROLE: Post-grad degree (MSc., PhD) in Chemistry, Pharmacy or other Natural Science degree with proficient program in organic chemistry with 8 year of relevant experience. Excellent theoretical knowledge of Organic chemistry and mechanisms of chemical reactions, advanced knowledge of medicinal chemistry advantageous. Proven track record as a successful synthetic Organic Chemist and other complex synthetic chemistry experience. Priority will be given to candidates with relevant industrial experience in the field of active pharmaceutical ingredient synthesis and PhD from the field of Organic or Medicinal chemistry.Why consider Sandoz Our number 1 priority is to pioneer patient access to better healthcare. We are a company of firsts. 1st to develop an oral penicillin antibiotic. 1st to develop and launch biosimilars. 1st to launch an FDA-cleared digital therapeutic. And we never stop asking: how can we continue to pioneer access in an ever-more digital and global world The answers come when curious, courageous and collaborative people are empowered to ask new questions, make bold decisions and take smart risks.Sandoz, a Novartis division, is a leader in generic and biosimilar medicines and a pioneer in digital therapeutics.Imagine what you could do at Sandoz!Commitment to Diversity & Inclusion:Sandoz, a Novartis company, embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.,

Keyskills :
high quality standardsglobal teamsorganic chemistryquality standardschemical synthesisfeasibility studiesintellectual propertyhseapitrustsupplyaccesssciencecontrol