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Tech Lead - Process R&D API

9.00 to 12.00 Years   Hyderabad   02 Sep, 2020
Job LocationHyderabad
EducationNot Mentioned
SalaryNot Disclosed
IndustryPharma / Biotech
Functional AreaBio Tech / R&D / Scientist
EmploymentTypeFull-time

Job Description

Process Chemistry : Exposure to synthetic organic chemistry & physical organic chemistry, process development, organometallic chemistry and catalysis.Strategy design :Lead the team to screen, validate and execute routes for APIs Identify challenges and propose alternatives that are cost-effective, efficient and preferably green RoS Generate final route selection document and product strategy report Perform literature studies and evaluate data to summarise the route selection strategy and identify challenges Identify the cost effective routes and IP compliant routes Process development and optimisation : Lead planning for process development and execute experiments for HPTs adopting QbD approach. Develop scalable and robust processes integrating chemistry and unit operations Coordinate with MSAT team to ensure compliance and timely execution in terms of QbD elements, safety and project deliverables Monitor and review the progress of the project Collaborate with the team to synthesise challenging impurities and to prepare degradation pathways Functional knowledge : Expertise in organic chemistry with deep understanding of reaction mechanisms, by products and possible side reactions Understand analytical techniquesProcess scale up & validation : Lead tech transfer for multiple projects Monitor progress of plant performance as compared to lab performance for multiple projects Anticipate and address issues in batch failures and design the studies/experiments to resolve the issues Collaborate with CFTs to finalise deviation and investigation reportsMust have experiences : Developed and delivered having worked end to end for at least 2-3 new products/solutionsPart of process development/scale-up across 8-10 projectsPublished and presented research papers in reputed journals/ national & international forums ,

Keyskills :
physical organic chemistrysynthetic organic chemistrytech transfercost effectiveunit operationsproduct strategyorganic chemistryprocess developmentorganometallic chemistrystatements of work sow

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