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Associate Scientist- Cell and Assay Biologist 1

2.00 to 5.00 Years   Kolkata   19 Apr, 2021
Syngene International Limited
Job LocationKolkata
EducationNot Mentioned
SalaryNot Disclosed
IndustryEducation / Training
Functional AreaGeneral / Other Software,Bio Tech / R&D / Scientist
EmploymentTypeFull-time

Job Description

Designation: Senior Associate Scientist/Senior Research AssociateJob Location: BangaloreDepartment: Discovery BiologyAbout SyngeneIncorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.Job Purpose:To be a part of the Assay Biology and Screening group and support various assay development activities.Key Responsibilities:

  • To develop cell-based assays- optimization and assay validation in 96- and 384-well formats using different technologies
  • Biochemical, Enzyme based assay development
  • Screening of the compounds- small and large molecules.
  • Data analysis, contemporaneous documentation and report preparation
  • Interacting and presenting the data to the clients wherever needed
  • Possess the knowledge and exposure to environment, health, and safety (EHS) practices
  • Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety.
Educational Qualification:
  • M.Sc/M.Tech/M.Pharm in Biological Sciences/ Biochemistry/ Biotechnology/ Cell Biology
Technical/functional Skills:
  • Experience with conducting assays in 96-well and/or 384-well formats
  • Experience with screening compounds in the dose-response formats for determining the potency of the compounds.
  • Experience in conducting TR-FRET, HTRF, Fluorescence Intensity, Alpha screen, Radioactive assays OR Luminesce based assay.
  • Expertise and in-depth knowledge of mammalian cell culture, with primary cells (hepatocytes, nerve cells or stem cells) and cancer cell lines
  • Experience in different cell based assays viz. cytotoxicity assays, cytokine release assays, qPCR, Western blots is required
  • Experience with spheroid cultures and 3D models would be desirable
  • Experience in Flow cytometry and immune-phenotyping would be desirable
  • Ability to analyze and present data using GraphPad Prism; MS Excel, ppt and statistical tools
  • Willingness and flexibility to work in cross functional teams across technical domains
  • Ability to plan and execute work and perform multiple activities in parallel.
Experience:
  • M.Sc/M.Tech or M.Pharm with 2 to 9 years of experience
Behavioral Skills:
  • Good work ethics.
  • Good interpersonal skills, and the ability to work effectively in a team environment.
  • Ability to work with coworkers professionally.
  • General ability to thrive in a growing infrastructure and culture and also think out of box approach when troubleshooting and problem solving.
Equal Opportunity Employer:It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.,

Keyskills :
continuous improvement facilitationcell based assaysdocumentationcell cultureequal employment opportunityprotocolsanimal healthmammalian cell cultureconsumer goodsprimary cells

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