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Senior Associate Scientist- Immunology

4.00 to 8.00 Years   Kolkata   20 Apr, 2021
Syngene International Limited
Job LocationKolkata
EducationNot Mentioned
SalaryNot Disclosed
IndustryEducation / Training
Functional AreaOperations Management / Process Analysis
EmploymentTypeFull-time

Job Description

Designation: Senior Associate Scientist/Senior Research Associate- ImmunologyJob Location: BangaloreDepartment: Discovery BiologyAbout SyngeneIncorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.Job PurposeThe incumbent will support the Translational team for various immunology/Immuno-oncology (IO) projects and will be responsible for the execution of planned experiments with high quality. Key Responsibilities:

  • Development of the assays using primary immune cells, tumor cells and cell lines for relevant endpoints (e.g. cytotoxicity, cytokine release, binding) with screening of the small or large molecules
  • Isolation and enrichment of human (and/or mouse) primary immune cells (T cells, B cells, NK cells, Macrophages etc).
  • The successful candidate will work extensively with primary/immune cells or iPSCs or CAR-Ts for T- cell activation; B-cell activation; Macrophage and other myeloid lineage cell based assays
  • Analysis, contemporaneous documentation and timely communication of compiled data.
  • Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab safety
Educational Qualification:
  • M.Sc/M.Tech in Life sciences/Immunology/Cell biology
Technical/functional Skills:
  • Good experience in immunology particularly dealing with human or mouse primary T cells, B-cells, NK cells or Macrophages or neutrophils
  • Sound knowledge of Multi-color flow cytometry based immune phenotyping (highly preferred).
  • Experience with cell proliferation/cytotoxicity assays; cell based binding assays and/or
  • cytokine release assays (both intracellular and soluble formats) in 96-well or 384-well formats
  • Must have experience with different cancer cell lines of various origins.
  • Experience with other primary cells, ES cells/iPSCs is desirable but not mandatory.
  • Experience with transfection and/or transduction of Primary cells (T- cells) and cell lines.
  • Experience with Real time PCR, ELISA, Western blotting is desirable
  • Excellent attention to experimental details, data documentation and clear communication of compiled data to team members.
  • Excellent verbal/written communication and ability to communicate effectively with high transparency is essential.
  • Computer proficiency including the use of spreadsheet and word processing software, such as GraphPad Prism; Microsoft Word,Excel and Power point.
Experience:
  • M.Sc or M.Tech or M.Pharm with 4-12 years post qualification
Behavioral Skills:
  • Good work ethics.
  • Good interpersonal skills, and the ability to work effectively in a team environment.
  • Ability to work with coworkers professionally.
  • General ability to thrive in a growing infrastructure and culture and also think out of box approach when troubleshooting and problem solving.
Equal Opportunity Employer:It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.,

Keyskills :
benefits administrationmarketingequal employment opportunityresearchcontinuous improvement facilitationcell linesquality controlreal time pcrprimary cellsauditinganimal healtht cellsmulticolor flow cytometry

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