Needs for Senior research scientist

Job Description

Designation: Senior Research ScientistJob Location: Bengaluru, IndiaReporting to: Principal Scientist, Technology TransferJob Grade: 7-IIOperating Unit : Chemical DevelopmentDepartment: Technology TransferThe CompanySyngene International Ltd. (BSE: 539268, NSE: SYNGENE, ISIN: INE398R01022), is an integrated research, development and manufacturing services company serving the global pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical sectors. Syngene s 4500+ scientists offer both skills and the capacity to deliver great science, robust data management and IP security and quality manufacturing, at speed, to improve time-to-market and lower the cost of innovation. With a combination of dedicated research facilities for Amgen, Baxter, Bristol-Myers Squibb and Herbalife, as well as 1.9 Mn sq ft of specialist discovery, development and manufacturing facilities, Syngene works with biotech companies pursuing leading edge science as well as multinationals including GSK and Merck KGaA.The RoleThe role is will work in Technology transfer team and he should interact with Process R&D to absorb the knowledge of chemistry involved in the project. He/She should perform few familiarization reactions and to make the documents for scale up batch at manufacturing facility. Also monitor the batch and understand the gap in the process on scale and do the trouble shooting work whenever required. The candidate should actively work in shop floor of scale up facility while execution and lab optimization reactionsKey Result AreasRole-specific:
• Basic understanding of chemistry and knowledge on different types of reactions.
• Performing lab experiments and interpretation skills on the analytical data like NMR, Mass etc.
• LNB writing skills and preservation of the records as per the requirement
• Anticipate scale up challenges and identify possible areas of improvement towards process robustness
• Knowledge on scale up pilot plant and trouble shooting
• Knowledge on document compliance to cGMP batches.
• OOT, OOS and deviation closure - basic knowledge
• Process excellency, de-bottlenecking to retrofit / capacity enhancement and cost reduction
• Lab safety practices and knowledge on fire hydrants, masks etc.
• Working in shifts depends on the requirement
• Project update and client communication
• Preparation of campaign report and investigation report
• Possess the knowledge and exposure to Environment, Health, Safety, and Sustainability (EHSS) practices.
• Follow Environment, Health, Safety, and Sustainability (EHSS) requirements at all times in the workplace ensuring individual and lab/plant safety.
• Attend training on Environment, Health, Safety, and Sustainability (EHSS)
Education and ExperienceEducationPhDIndustry Experience9-12 years of relevant experienceOther competencies required for the role
• Experience in Process Development and Scale up.
• Carrying out reactions, cost optimization, troubleshooting, updates, documentation activities in compliance with GDP & Data Integrity policy and support manufacturing operations in compliance with cGMP.
• Technical support like attending TC, customer meetings.
• Alignment and monitoring of PRD team to support lab and plant batches.
• Preparation of working standards and impurities to support QC requirements.
• Handling of documents like Costing sheet preparation, Change controls, TTD, BMR, deviations, CAPA & risk assessments for various reactions
• Excellent communication (Oral and written)
• Good Knowledge on regulatory and quality compliance in terms of equipment/ instrument.
Equal Opportunity EmployerIt is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.,

Keyskills :
technology transferhplcvalidationapi